Microscopy image files for "An allosteric theory of transcription factor induction."
Description
These data correspond to the raw microscopy images used to quantify fluorescence and compute the fold-change in gene expression due to the activity of the Lac repressor molecule in E. coli cells. These images were passed through an image analysis pipeline which segmented individual cells and computed the mean pixel value for each cell. This information was then used to compute the population average to be used in the determination of fold-change. These data are separated by the operator we examined. Eight different strains were measured for each dataset. Please see the main text or the paper website at http://rpgroup-pboc.github.io/mwc_induction for more information. Note that each image file has its own folder. These folder names are correct fore each collected image, however the image name differs on a few occasions. "
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Related Publication: An allosteric theory of transcription factor induction Manuel Razo-Mejia Caltech Stephanie L. Barnes Caltech Nathan M. Belliveau Caltech Griffin Chure Caltech Tal Einav Caltech Rob Phillips Caltech https://doi.org/10.1101/111013 eng
Additional details
- CALTECHDATA_ID
- 229
- :unav DPI OD000217
- National Institutes of Health
- :unav R01 GM085286
- National Institutes of Health
- :unav GM118043-01 (MIRA)
- National Institutes of Health