Published 2014 | Version v1
Dataset Open

CLEM of TRIM5a-YFP in HeLa cells

  • 1. ROR icon California Institute of Technology

Description

HeLa cells expressing stable TRIM5a-YFP. Correlated light electron microscopy. Concentration of red 200 nm beads 1/300. 10 nm gold. Manual blotting. Cells grown on grids for 2 days and look vesiculated.

Technical info

Tilt Series Date: 2014-06-17

Data Taken By: Stephen Carter

Species / Specimen: Hela cells expressing TRIM5a-YFP

Strain:

Tilt Series Settings: Single Axis, tilt range: (-60.0°, 60.0°), step: 1°, constant angular increment, dosage: 136.0 eV/Ų, defocus: -10.0 μm, magnification: 18000x.

Microscope: Caltech Polara

Acquisition Software: Undefined

Upload Method: pipeline

Processing Software Used: IMOD and Raptor

Collaborators and Roles: Tom Hope and Wes Sundquist

Purification / Growth Conditions / Treatment: Gold London finder grids glow discharged twice. Concentration of red 200 nm beads 1/300 on grid. 10 nm gold. Manual blotting. Cells grown on grids for 2 days and look vesiculated.

Attached Files

tomography10.mrc, Tilt Series (Pixel Size 0.6 nm), 3.4 GB

tomography10_full.rec, Reconstruction (Pixel Size 2.4 nm), 445.4 MB

Files

keyimg_scd2014-06-17-1.jpg

Files (3.9 GB)

Name Size
md5:7860ffc1977e28f7f2784f474b7a6471
1.0 MB Preview Download
md5:d6973fa4da1f70cfbd7cf30c07984d5c
15.0 MB Preview Download
3.4 GB (external) Download
445.4 MB (external) Download

Additional details

Identifiers

DOI
10.22002/nc8j6-jrh06
TILT_SERIES_ID
scd2014-06-17-1

Funding

NIH
HHMI
Beckman Institute
Gordon and Betty Moore Foundation
Agouron Institute
John Templeton Foundation

Dates

Collected
2014-06-17
Created
2014-06-25
Updated
2015-05-05