Table S1

The analysis presented in this document is use to demo the code for the R package tidyproteomics. The underlying data is based on previously published and publicly available data [1]. Raw data was analyzed using ProteomeDiscoverer 2.5, FragPipe 19.1, and MaxQuant 1.6.10.43 with basic settings for mass tolerance and PTMs. The exported results are...

Matrix stiffening is a quintessential feature of aged tissues. Authors show that an aged (stiff) matrix epigenetically represses the gene encoding the longevity factor, α-Klotho, resulting in chondrocyte dysfunction, a leading cause of osteoarthritis.

Chronic respiratory infection by polymicrobial communities is the leading cause of mortality and morbidity in people living with cystic fibrosis (CF). Here, we dissected molecular mechanisms of interspecies sensing between two notorious opportunistic pathogens dominating chronic CF infection, the Gram-negative Pseudomonas aeruginosa and the Gram...