August 29, 2020 (1.0)
Dataset
Open
Synthetic mammalian signaling circuits for robust cell population control
Synthetic signaling circuits could allow engineered cells to sense and control their own population density. The ideal circuit would operate independently of endogenous pathways and be robust to selection pressure for mutations that allow cells to evade population size limits. Here, we show that the plant hormone auxin can be repurposed as an or...
Uploaded on September 12, 2022